By comparing diseases from then and now, researchers can learn how they spread. Maybe they can learn how to stop them, too.
By Roxanne Khamsi
Earlier this year, scientists published a study of whole-body CT scans of 137 mummies: ancient Egyptians and Peruvians, ancestral Puebloans of southwest America, and Unangan hunter-gatherers of the Aleutian Islands. They reported signs of atherosclerosis—a dangerous artery hardening that can lead to heart attacks or stroke—in 34 percent of them. What struck the research team, led by Randall Thompson of Saint Luke's Mid America Heart Institute in Kansas City, Missouri, was that it afflicted mummies from every group. Frank Rühli, head of the Swiss Mummy Project at the University of Zurich, also sees the condition in about 30 to 50 percent of the adult specimens he studies. The breadth of these findings suggests that atherosclerosis today may have less to do with modern excesses such as overeating and more with underlying genetic factors that seem present in a certain percentage of humans living almost anywhere in the world. Someday, identifying those genes could lead to new drugs for heart disease.
Ancient mummies can provide a wealth of information about the health of early civilizations, which may help us better treat diseases today. But because mummies are both rare and delicate, researchers have been limited in what they could do to them—and therefore what they could learn from them. Recent improvements of two medical tools—DNA sequencing, which can reveal microbial infections, and CT scanning—are letting paleopathologists diagnose mummies' causes of death in detail. They're now finding signs of everything from prostate cancer to malaria in mummies across the globe. By comparing the ancient forms of those diseases with their contemporary equivalents, researchers can learn how those diseases evolved, what makes them so harmful, and—possibly—how to stop them.
